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Endometrial Hyperplasia

What is Endometrial Hyperplasia?


Endometrial Hyperplasia is a condition in which the lining of the uterus (endometrium) becomes abnormally thick due to excess estrogen stimulation without adequate progesterone balance. This hormonal imbalance causes the endometrial cells to proliferate excessively, which can lead to abnormal uterine bleeding and, in some cases, increase the risk of endometrial cancer.

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The condition can be classified into simple or complex hyperplasia, with or without atypia (abnormal cells). Atypical forms carry a higher risk of progressing to cancer.


Types of Endometrial Hyperplasia:

  • Simple (without atypia): mild thickening with normal cells, low cancer risk

  • Complex (without atypical): more gland crowding with low cancer risk

  • Simple atypical: mild thickening with abnormal cells, moderate cancer risk

  • Complex atypical: dense glandular growth with abnormal cells, high risk of cancer progression

What are common symptoms of Endometrial Hyperplasia?


Common symptoms:

  • Heavy or prolonged menstrual bleeding

  • Bleeding between periods

  • Short menstrual cycles (<21 days)

  • Postmenopausal bleeding

  • Amenorrhea (absence of periods)

References:

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